1) Cat. No.: TRC-C175152; 2) Chemical Name: (S)-(+)-Camptothecin-d5; 3) CAS No.: ; 4) Mol. Formula: C20H11D5N2O4; 5) Mol. Weight: 353.38; 6) Packing Size: 1mg / 10mg; 7) Appearence: ; 8) Application Notes: Labelled (S)-(-)-Camptothecin (C175150). Antitumor alkaloid. Binds irreversible to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA. A cytotoxic antitumor agent.; 9) Synonym: (S)-4-(Ethyl-d5)-4-hydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione;; 10) Solubility: ; 11) Storage condition: ; 12) References: Potmesil, M., et al.: Cancer Res., 54, 1431 (1994), Desai, S.D., et al.: J. Biol. Chem., 272, 24159 (1997), Fan, Y., et al.: J. Med. Chem., 41, 2216 (1998),  Kaufmann, S.H., et al.: Biochim. Biophys. Acta, 1400, 195 (1998),